产品货号:
Z11291
中文名称:
Apc2/ANAPC2抗体
英文名称:
Anti-Apc2/ANAPC2 Antibody
产品规格:
100μl
发货周期:
1~3天
产品价格:
询价
抗体名称 | Anti-Apc2/ANAPC2 Antibody |
指标别名 | ANAPC2;APC2;Cyclosome subunit 2;KIAA1406;RP11 350O14.5 |
克隆性 | Polyclonal |
检验物种 | human |
应用范围 | IHC,WB |
基因名称 | ANAPC2 |
抗体来源 | Rabbit |
抗体类型 | IgG |
免疫原 | This antibody was prepared from whole rabbit serum produced by repeated immunizations with a synthetic peptide corresponding to amino acids 810-822 of Human APC2 (C-terminal) coupled to KLH. |
成分 | 0.01% (w/v) Sodium Azide |
纯化方式 | This product is monospecific antiserum processed by delipidation and defibrination followed by sterile filtration.This product reacts with human APC2.Cross-reactivity may also occur with APC2 from other sources.Sufficient sequence differences exist to suggest that this antibody would not react with other RING box proteins such as ROC1 and ROC2. |
浓度 | 85mg/mL by Refractometry |
产品形态 | 溶液 |
保存条件 | Store vial at -20℃ prior to opening.Aliquot contents and freeze at -20℃ or below for extended storage.Avoid cycles of freezing and thawing.Centrifuge product if not completely clear after standing at room temperature.This product is stable for several weeks at 4℃ as an undiluted liquid.Dilute only prior to immediate use.Expiration date is one (1) year from date of opening. |
背景资料 | APC2,also known as Anaphase promoting complex subunit 2,APC2,Cyclosome subunit 2,and ANAPC2,is a component of the anaphase promoting complex/cyclosome (APC/C),a cell cycle-regulated E3 ubiquitin ligase that controls progression through mitosis and the G1 phase of the cell cycle.The APC/cyclosome protein complex promotes metaphase-anaphase transition by ubiquitinating its specific substrates such as mitotic cyclins and anaphase inhibitors,which are subsequently degraded by the 26S proteasome.Biochemical studies have shown that the vertebrate APC contains at least eleven subunits.The composition of APC is highly conserved in organisms from yeast to humans.APC2 is a cullin family member that interacts through the cullin domain with ANAPC11 and UBCH10. |
Uniprot ID | Q9UJX6 |
推荐稀释比 | ELISA:1:2,000 - 1:10,000 IHC:User Optimized WB:1:500 - 1:1,000 |
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